Laurent Lecanu Selected Research

25R)-20alpha-spirost-5-en-3beta-yl hexanoate (22R

3/2009	Caprospinol: moving from a neuroactive steroid to a neurotropic drug.
8/2006	The spirostenol (22R, 25R)-20alpha-spirost-5-en-3beta-yl hexanoate blocks mitochondrial uptake of Abeta in neuronal cells and prevents Abeta-induced impairment of mitochondrial function.

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Laurent Lecanu Research Topics

Disease

12	Alzheimer Disease (Alzheimer's Disease) 02/2018 - 12/2003
3	Neoplasms (Cancer) 03/2011 - 04/2008
2	Neurodegenerative Diseases (Neurodegenerative Disease) 01/2011 - 06/2007
2	Neuroblastoma 01/2011 - 08/2006
2	Acquired Immunodeficiency Syndrome (AIDS) 09/2009 - 12/2003
2	Hypertension (High Blood Pressure) 09/2009 - 12/2003
1	Atherosclerotic Plaque (Atheroma) 02/2013
1	Atherosclerosis 02/2013
1	Hypercholesterolemia 02/2013
1	Amyloid Plaque 01/2006
1	Gliosis 01/2006
1	Memory Disorders (Memory Loss) 01/2006
1	Pheochromocytoma 05/2005
1	Hepatocellular Carcinoma (Hepatoma) 12/2003

Drug/Important Bio-Agent (IBA)

4	Pharmaceutical PreparationsIBA 02/2018 - 06/2007
3	Amyloid beta-PeptidesIBA 01/2006 - 05/2005
2	CholesterolIBA 02/2013 - 03/2009
2	NeurosteroidsIBA 01/2011 - 03/2009
2	Dehydroepiandrosterone (DHEA)IBA 01/2011 - 01/2011
2	Amyloid (Amyloid Fibrils)IBA 01/2011 - 05/2005
2	GlucocorticoidsIBA 09/2009 - 12/2003
2	SteroidsIBA 09/2009 - 03/2009
2	BucladesineIBA 09/2009 - 12/2003
2	22-hydroxycholesterolIBA 03/2009 - 01/2004
2	25R)-20alpha-spirost-5-en-3beta-yl hexanoate (22RIBA 03/2009 - 08/2006
2	Peptides (Polypeptides)IBA 01/2006 - 05/2005
2	Procaine (Novocaine)FDA LinkGeneric 05/2005 - 12/2003
1	LDL CholesterolIBA 02/2013
1	Proteins (Proteins, Gene)FDA Link 02/2013
1	cholesterol-binding proteinIBA 02/2013
1	LipidsIBA 02/2013
1	valyl- leucyl- asparagyl- tyrosyl- tyrosyl- valyl- tryptophanIBA 03/2011
1	Adenylate KinaseIBA 01/2011
1	EnzymesIBA 01/2011
1	EstersIBA 05/2010
1	carbamic acid (ammonium carbamate)IBA 05/2010
1	Biological ProductsIBA 05/2010
1	Adrenal Cortex Hormones (Corticosteroids)IBA 09/2009
1	benzamideIBA 09/2009
1	CorticosteroneIBA 09/2009
1	TubulinIBA 04/2008
1	oxophenylarsine (phenylarsine oxide)IBA 08/2006
1	Neuroprotective AgentsIBA 08/2006
1	thioflavin TIBA 01/2006
1	tau Proteins (tau Protein)IBA 01/2006
1	AntioxidantsIBA 01/2006
1	Adenosine Triphosphate (ATP)IBA 05/2005
1	amyloid beta-protein (1-42)IBA 05/2005
1	Local AnestheticsIBA 05/2005
1	Messenger RNA (mRNA)IBA 12/2003
1	Hydroxymethylglutaryl CoA Reductases (HMG CoA Reductase)IBA 12/2003

Therapy/Procedure

2	Therapeutics 04/2008 - 01/2004